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KMID : 0377519790040010001
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Chung-Ang Journal of Medicine
1979 Volume.4 No. 1 p.1 ~ p.6
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Effect of Ethanol on Juxtaglomerular Granular Cell of Mouse
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Rah Bong-Jin
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Abstract
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The relationship between ethyl alcohol, injected intraperitoneally, and juxtaglomerular granular cell was studied by the calculation of granular cell index and juxtaglomerular granular index under light microscope. The histological slides were prepared according to Smith’s modification of Bowie’s method after fixing in Smith’s fluid. The results obtained are as follows: 1. The granular cell indices of the experimental groups which were injected with ethyl alcohol in doses of 3 and 9gm/㎏ body weight were both increased. In case of 3 gm-injected group shows slightly increasing tendency in proportion to time sequence. 2. The juxtaglomerular index of 3 gm-injected group was increased proportionately up to three hours after administration, and that of 9 gm-injected group showed the abrupt increase until one hour later. 3. The most frequently appearing cell type is type Ⅰ cell, and type Ⅱ cell the next. Type Ⅲ and Ⅳ cells were appeared in a very few number. The above results showed that the increase in juxtaglomerular granular index might be caused by the metamorphosis of the other cell types in the juxtaglomerular apparatus into juxtaglomerular granular cells.
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